About Olfax

Focused on the Trigeminal Nerve. Committed to Patients in Pain.

Olfax Medical is a clinical-stage biopharmaceutical company developing therapeutics for patients living with trigeminal-mediated pain — including cluster headache, migraine, post-traumatic headache, and trigeminal neuralgia. Our mission is to give patients fast, direct relief from these conditions without the delay, side effects, or dependency risk of systemic pharmaceuticals.

Founded in 2020, our team is translating a well-established interventional procedure — sphenopalatine ganglion (SPG) block — into a therapeutic option patients can administer themselves, at the onset of an attack.

Company History

Clinical Innovation. Into the Hands of Patients.

Our core innovation was born from clinical practice and over a decade of evaluating, treating, and managing patients with neurological disorders — individuals dealing not only with chronic pain but chronic frustration from a lack of effective, tolerable treatment options.

Nearly a decade before Olfax Medical was founded, our founder, Dr. Jason Cook, first began performing sphenopalatine ganglion (SPG) block procedures in an attempt to curb opioid use in the treatment of acute migraine while working as a primary care physician for the National Health Service Corps.  When he first joined a rural clinic within one of the most economically disadvantaged counties in North Carolina, opioid injections were the most common treatment for patients presenting with acute, intractable migraine — many patients and providers assumed they were the only option for migraine unresponsive to NSAID or triptan therapy. By performing SPG blocks in clinic, Dr. Cook reduced opioid use and changed the culture around acute migraine care in the region — and began to see the same underlying pathway at work across a wider range of trigeminal-mediated pain conditions.

What started as a clinical passion has since evolved into a company translating that same procedure into a self-administered therapeutic, bringing it from the clinic into the hands of patients.